Anti-Human/Mouse ADAMTS17 Polyclonal Antibody

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10026
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human ADAMTS17
Specificity Isoform 1 and isoform 2 are expressed at high levels in the lung, brain, whole eye and retina. Isoform 1 shows a weaker expression in the heart, kidney and skeletal muscle. Isoform 2 shows a weaker expression in the kidney, bone marrow and skeletal muscle. Isoform 1 and isoform 2 are expressed at high levels in the fetal heart, kidney, and whole eye, whereas a weak expression is seen in the fetal liver.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8TE56
Concentration 0.7 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names A disintegrin and metalloproteinase with thrombospondin motifs 17,A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif,17,ADAM metallopeptidase with thrombospondin type 1 motif,17,ADAM-TS 17,ADAM-TS17,ADAMTS 17,ADAMTS-17,ADAMTS17,ATS17,EC 3.4.24.,FLJ16363,FLJ32769,OTTHUMP00000194818
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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