Anti-Human/Mouse ADAM12 Polyclonal Antibody

This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10032
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human ADAM12
Specificity Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O43184
Concentration 0.3 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names A disintegrin and metalloproteinase domain 12,ADA12,ADAM 12,ADAM metallopeptidase domain 12,ADAM12,CAR10,Disintegrin and metalloproteinase domain-containing protein 12,MCMP,MCMPMltna,Meltrin alpha,Meltrin-alpha,Metalloprotease disintegrin 12 transmembrane,MLTN,MLTNA,OTTHUMP00000046766
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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