Anti-Human/Monkey DR4 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA03589
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the C-terminal region of human DR4
Specificity	Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K562 erythroleukemia cells, MCF7 breast carcinoma cells and activated T-cells.
Isotype	IgG
Reacitivity	Human,Monkey
Clone
Uniprot	O00220
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:5000
Formulation
Application	WB,IF,ELISA
Other Names	Apo2,CD261,Cytotoxic TRAIL receptor,Death receptor 4,DR4,NF related apoptosis-inducing ligand receptor 1,TNF receptor superfamily member 10a,TNF-related apoptosis-inducing ligand receptor 1,TNFRSF10A,TR10A,TRAIL receptor 1,TRAIL-R1,TRAILR 1,TRAILR1,Tumor necrosis factor receptor superfamily member 10A,Tumor necrosis factor receptor superfamily member 10a variant 2,Tumor necrosis factor receptor superfamily,member 10a
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Monkey DR4 Polyclonal Antibody

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