Data Sheet | Click for Datasheet |
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Catalog Number | PA02169 |
Size | 100μl |
Host Type | Rabbit |
Immunogen | Synthesized peptide derived from the C-terminal region of human Tumstatin |
Specificity | Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. According to PubMed:8083201, alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. According to PubMed:7523402, alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3. Isoform 1 and isoform 3 are expressed at low levels in artery, fat, pericardium and peripherical nerve, but not in placenta, mesangium, skin, pleura and cultured umbilical endothelial cells. |
Isotype | IgG |
Reacitivity | Human,Monkey |
Clone | |
Uniprot | Q01955 |
Concentration | 1mg/mL |
Dilution | WB 1:500-1:2000, ELISA 1:40000 |
Formulation | Application | WB,ELISA |
Other Names | Alpha 3 type IV collagen,Alpha3 type IV collagen,CO4A3,COL4A 3,Col4a3,Collagen alpha 3(IV) chain,Collagen IV alpha 3 polypeptide,Collagen type IV alpha 3 (Goodpasture antigen),Collagen type IV alpha 3,Collagen type IV alpha 3 chain,Goodpasture antigen,OTTHUMP00000195044,Tumstatin |
Storage | Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C. |
Postscript | For research use only, not for use in diagnostic procedures. |
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