Anti-Human/Monkey AVEN Polyclonal Antibody

Aven binds to both Bcl-x(L) and the caspase regulator Apaf-1,which can supported that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway.Identified in a yeast two-hybrid screen,Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus .
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02209
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Aven
Specificity Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.
Isotype IgG
Reacitivity Human,Monkey
Clone
Uniprot Q9NQS1
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names 1700013A01Rik,1700056A21Rik,Apoptosis caspase activation inhibitor,AVEN,AVEN,Cell death regulator Aven,mAven L,mAven S,MGC124011,OTTMUSP00000016129,PDCD12,Programmed cell death 12,RP23-52C15.2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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