Anti-Human/Monkey ARHGEF10 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA02085
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the Internal region of human ARHGEF10
Specificity
Isotype	IgG
Reacitivity	Human,Monkey
Clone
Uniprot	O15013
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application	WB,IHC-p,ELISA
Other Names	ARHGA,ARHGEF10,DKFZp686H0726,GEF10,KIAA0294,MGC131664,Rho guanine nucleotide exchange factor (GEF) 10,Rho guanine nucleotide exchange factor 10
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Monkey ARHGEF10 Polyclonal Antibody

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