Anti-Human MAGEA1 Polyclonal Antibody

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04818
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human MAGE-1
Specificity Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
Isotype IgG
Reacitivity Human
Clone
Uniprot P43355
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names Antigen MZ2 E,Antigen MZ2-E,Cancer/testis antigen 1.1,cancer/testis antigen family 1,member 1,CT1.1,MAGA1,MAGE 1 antigen,MAGE-1 antigen,MAGE1,MAGE1A,MAGEA1,Melanoma antigen 1,Melanoma antigen family A 1 (directs expression of antigen MZ2 E),Melanoma antigen family A 1,Melanoma antigen MAGE 1,Melanoma associated antigen 1,Melanoma associated antigen MZ2 E,Melanoma-associated antigen 1,MGC9326
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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