Anti-Human LTB4DH Polyclonal Antibody

This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants.PTGR1 (Prostaglandin Reductase 1) is a Protein Coding gene. Among its related pathways are Arachidonic acid metabolism and NRF2 pathway. GO annotations related to this gene include oxidoreductase activity and 13-prostaglandin reductase activity. An important paralog of this gene is PTGR2.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04781
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human LTB4DH
Specificity High expression in the kidney, liver, and intestine but not in leukocytes.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q14914
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:5000
Formulation
Application WB,ELISA
Other Names 15-oxoprostaglandin 13-reductase,FLJ99229,leukotriene B4 12-hydroxydehydrogenase,LTB4DH,MGC34943,NADP-dependent leukotriene B4 12-hydroxydehydrogenase,PGR1,PRG-1,Prostaglandin reductase 1,Ptgr1,PTGR1,RP11-16L21.1,ZADH3,zinc binding alcohol dehydrogenase domain containing 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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