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Anti-Human LILRB1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06521
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human LIR-1.
Specificity Expressed predominantly on B-cells and monocytes, and at lower levels on dendritic cells. Detected on a low percentage of T-cells and natural killer (NK) cells.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q8NHL6
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names CD85,CD85 antigen,CD85 antigen like family member J,CD85 antigen-like family member J,CD85j,CD85j antigen,Ig like transcript 2,ILT 2,ILT-2,ILT2,immunoglobulin like transcript 2,Immunoglobulin-like transcript 2,leukocyte Ig like receptor 1,Leukocyte immunoglobulin like receptor 1,leukocyte immunoglobulin like receptor subfamily B member 1,Leukocyte immunoglobulin like receptor subfamily B member 1 precursor,leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin like receptor,subfamily B,member 1,Leukocyte immunoglobulin-like receptor 1,Leukocyte immunoglobulin-like receptor subfamily B member 1,leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains),member 1,LILRB1,LIR 1,LIR-1,LIR1,LIRB1,MIR 7,MIR-7,MIR7,Monocyte/macrophage immunoglobulin like receptor 7,Monocyte/macrophage immunoglobulin-like receptor 7,PIR B,PIRB
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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