Anti-Human IL21R Polyclonal Antibody

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11515
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human IL21R
Specificity Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9HBE5
Concentration 0.2 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names CD360,IL 21R,IL-21 receptor,IL-21R,IL21 receptor,IL21R,IL21R,Interleukin 21 receptor,Interleukin-21 receptor,MGC10967,NILR,Novel interleukin receptor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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