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Anti-Human IL18R1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02574
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human IL-18R.
Specificity Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q13478
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names CD218 antigen-like family member A,CD218a,CDw218a,CDw218a antigen,IL 1Rrp,IL-18R-1,IL-18R1,IL-1Rrp,IL1 receptor related protein,IL1 receptor-related protein,IL18R,IL18R1,IL18RA,Il18ralpha,IL1R-rp,IL1RRP,Interleukin 18 receptor 1,Interleukin 18 receptor,alpha chain,Interleukin-18 receptor 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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