Anti-Human IFNAR1 Polyclonal Antibody

IFNAR1 (Interferon Alpha And Beta Receptor Subunit 1) is a Protein Coding gene. Diseases associated with IFNAR1 include Septicemic Plague and Hepatitis C. Among its related pathways are Type I Interferon Signaling Pathways and Immune response IFN alpha/beta signaling pathway. GO annotations related to this gene include interferon receptor activity and type I interferon receptor activity. An important paralog of this gene is ENSG00000249624.The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04764
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide from human protein
Specificity IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
Isotype IgG
Reacitivity Human
Clone
Uniprot P17181
Concentration 1mg/mL
Dilution IHC 1:50-200, ELISA 1:10000-20000
Formulation
Application IHC-p,ELISA
Other Names Alpha type antiviral protein,Antiviral protein,alpha-type,Antiviral protein,beta-type,AVP,Beta type antiviral protein,CRF2-1,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1,IFN alpha REC,IFN alpha receptor,IFN alpha/beta Receptor alpha,IFN beta receptor,IFN Interferon-beta receptor,IFN-alpha/beta receptor 1,IFN-R-1,IFNAR,Ifnar1,IFNBR,IFRC,INAR1,Interferon (alpha beta and omega) receptor 1,interferon alpha and beta receptor subunit 1,Interferon alpha/beta receptor 1,Interferon alpha/beta receptor alpha chain,Interferon beta receptor 1,interferon receptor 1,Interferon-alpha receptor,Type I interferon receptor 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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