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Anti-Human HSD17B1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09054
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human HSD17B1
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P14061
Concentration 0.5 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names 17 beta HSD 1,17 beta hydroxysteroid dehydrogenase type 1,17-beta-HSD 1,17-beta-hydroxysteroid dehydrogenase type 1,20 alpha-hydroxysteroid dehydrogenase,20-alpha-HSD,DHB1,E17KSR,E2DH,EDH17B1,EDH17B2,EDHB17,Estradiol 17 beta dehydrogenase 1,Estradiol 17-beta-dehydrogenase 1,HSD17,HSD17B1,Hydroxysteroid (17 beta) dehydrogenase 1,MGC13814,Placental 17 beta hydroxysteroid dehydrogenase,Placental 17-beta-hydroxysteroid dehydrogenase,SDR28C1,Short chain dehydrogenase/reductase family 28CE,member 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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