Anti-Human HMGCS2 Polyclonal Antibody

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10074
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human HMGCS2
Specificity High expression in liver and colon. Low expression in testis, heart, skeletal muscle and kidney.
Isotype IgG
Reacitivity Human
Clone
Uniprot P54868
Concentration 0.6 mg/mL
Dilution WB 1:200-1:1000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial),3 hydroxy 3 methylglutaryl Coenzyme A synthase 2,3 hydroxy 3 methylglutaryl coenzyme A synthase,3-hydroxy-3-methylglutaryl coenzyme A synthase,HMCS2,HMG CoA synthase,HMG-CoA synthase,HMGCS 2,HMGCS2,Hydroxymethylglutaryl CoA synthase,Hydroxymethylglutaryl CoA synthase mitochondrial,Hydroxymethylglutaryl-CoA synthase,mitochondrial
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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