Anti-Human HES6 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

HES6 is a transcription cofactor that iteself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumour and cancer cell lines, although these have not yet been elucidated fully.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA04381
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the N-terminal region of human HES-6
Specificity
Isotype	IgG
Reacitivity	Human
Clone
Uniprot	Q96HZ4
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application	WB,IHC-p,ELISA
Other Names	bHLHb41,bHLHc23,C HAIRY1,Class B basic helix-loop-helix protein 41,Hairy and enhancer of split 6,Hairy/enhancer of split 6,Drosophila,homolog of,6,HES 6,hes family bHLH transcription factor 6,Transcription cofactor HES6
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human HES6 Polyclonal Antibody

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