Anti-Human GPR18 Polyclonal Antibody

G protein coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR18 is a member of this family and has been reported to be expressed at high levels in testis and spleen and at lower levels in other tissues associated with endocrine and immunologic/hematologic functions. It is thought to be a receptor for N arachidonyl glycine. It may contribute to regulation of the immune system.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04288
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human GPR18
Specificity Expressed in midpiece of spermatozoon (at protein level) (PubMed:27572937). Most abundant in testis and spleen (PubMed:16844083). Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells (PubMed:16844083).
Isotype IgG
Reacitivity Human
Clone
Uniprot Q14330
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:40000
Formulation
Application WB,IF,ELISA
Other Names G protein coupled receptor 18,GPCRW,GPR 18,GPR18,N arachidonyl glycine receptor,NAGly receptor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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