Anti-Human GK1/3 Polyclonal Antibody

The protein encoded by GK belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. GK (Glycerol Kinase) is a Protein Coding gene. Diseases associated with GK include Glycerol Kinase Deficiency and Glycerol Kinase Deficiency, Adult Form. Among its related pathways are triacylglycerol biosynthesis and Glycerophospholipid Biosynthetic Pathway. GO annotations related to this gene include kinase activity and glycerol kinase activity. An important paralog of this gene is GK3P. GK3P (Glycerol Kinase 3 Pseudogene) is a Pseudogene. An important paralog of this gene is GK.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04201
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human GK1/3
Specificity Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.
Isotype IgG
Reacitivity Human
Clone
Uniprot
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Formulation
Application WB,IHC-p,ELISA
Other Names GK,Glycerol kinase,GK,Glycerokinase,ATP:glycerol 3-phosphotransferase,GK3P,GKP3,GKTB,Putative glycerol kinase 3,GK 3,Glycerokinase 3,ATP:glycerol 3-phosphotransferase 3,Glycerol kinase,testis specific 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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