Anti-Human GCSAM Polyclonal Antibody

This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09974
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human GCSAM
Specificity Expressed in diffuse large B-cell lymphoma (DLBCL) and several germinal center (GC)-like lymphoma cell lines (at protein level). Highly expressed in normal GC lymphocytes and GC-derived malignancies. Expressed in thymus and spleen.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q8N6F7
Concentration 1.1 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names GCAT2,Gcet,GCET2 germinal center expressed transcript 2,GCET2 germinal centre expressed transcript 2,Gcsam,GCSAM,Germinal center associated lymphoma,Germinal center associated lymphoma protein,Germinal center B cell associated protein 2,Germinal center B-cell-expressed transcript 2 protein,Germinal center expressed transcript 2,Germinal center-associated lymphoma protein,Germinal center-associated signaling and motility protein,Germinal centre associated lymphoma,Germinal centre associated lymphoma protein,Germinal centre B cell associated protein 2,Germinal centre expressed transcript 2,hGAL,M17,M17 L
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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