Anti-Human FTO Polyclonal Antibody

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12079
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human FTO
Specificity Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9C0B1
Concentration 0.4 mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300
Formulation
Application WB,IHC,ELISA
Other Names AlkB homolog 9,ALKBH9,Alpha-ketoglutarate-dependent dioxygenase FTO,AW743446,Fat mass and obesity-associated protein,FATSO,MOUSE,HOMOLOG OF,Fto,FTO,GDFD,KIAA1752,mKIAA1752,Protein fatso
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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