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Anti-Human FAIM3 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM. May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12118
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human FAIM3
Specificity Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat cells, CemT4 cells, MolT-4 cells, HB11.19 cells, and Reh cells. No expression detected in nonhematopoietic cell lines, including HepG2 cells, 293 cells and Hela cells.
Isotype IgG
Reacitivity Human
Clone
Uniprot O60667
Concentration 0.4 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names Faim3,FAIM3,Fas apoptotic inhibitory molecule 3,Fc fragment of IgM receptor,Fc mu receptor,FCMR,IgM Fc receptor,Immunoglobulin mu Fc receptor,Regulator of Fas induced apoptosis,Regulator of Fas-induced apoptosis Toso,TOSO
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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