Anti-Human EZR Polyclonal Antibody

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02025
Size 100μl
Host Type Rabbit
Immunogen Recombinant human EZR protein
Specificity Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
Isotype IgG
Reacitivity Human
Clone
Uniprot P15311
Concentration 2 mg/mL
Dilution WB 1:500-1:1000,IHC 1:50-1:100
Formulation
Application WB
Other Names Villin 2 ezrin,CVIL,CVL,Cytovillin 2,Cytovillin,DKFZp762H157,Epididymis secretory protein Li 105,EZR,EZRI,Ezrin,FLJ26216,HEL S 105,MGC1584,p81,VIL 2,VIL2,Villin 2 (ezrin),Villin 2,Villin-2,Villin2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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