Anti-Human EID1 Polyclonal Antibody

Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03696
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human EID-1
Specificity Widely expressed. Most abundantly expressed in heart, skeletal muscle, pancreas, brain and testis. Expressed at much lower levels in placenta and peripheral blood leukocyte. Barely detectable in lung. Also weakly expressed in lung carcinoma A549 and various leukemia cell lines.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9Y6B2
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names 21 kDa pRb associated protein,21 kDa pRb-associated protein,C15orf3,CBP,Chromosome 15 open reading frame 3,CREBBP/EP300 inhibitor 1,CREBBP/EP300 inhibitory protein 1,CRI 1,CRI1,E1A like inhibitor of differentiation,E1A-like inhibitor of differentiation 1,EID 1,EID-1,EID1,EID1,EP300 interacting inhibitor of differentiation 1,EP300-interacting inhibitor of differentiation 1,IRO45620,MGC138883,MGC138884,NB4 apoptosis related protein,PNAS 22,PNAS22,PTD014,Rb and p300 binding protein EID 1,Rb and p300 binding protein EID1,RBP21,Retinoblastoma protein associated protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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