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Anti-Human EDNRB Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11108
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human EDNRB
Specificity Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells.
Isotype IgG
Reacitivity Human
Clone
Uniprot P24530
Concentration 0.4 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names ABCDS,Ednra,EDNRB,EDNRB,Endothelin B receptor,Endothelin B receptor precursor,Endothelin receptor Non selective type,Endothelin receptor non-selective type,Endothelin receptor type B,ET B,ET-B,ET-BR,ETB,ETBR,ETRB,Hirschsprung disease 2,HSCR,HSCR2,OTTHUMP00000018534,OTTHUMP00000178736,WS4A
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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