Anti-Human DNMT1 Polyclonal Antibody

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11354
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human DNMT1
Specificity Ubiquitous; highly expressed in fetal tissues, heart, kidney, placenta, peripheral blood mononuclear cells, and expressed at lower levels in spleen, lung, brain, small intestine, colon, liver, and skeletal muscle. Isoform 2 is less expressed than isoform 1.
Isotype IgG
Reacitivity Human
Clone
Uniprot P26358
Concentration 0.3 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names ADCADN,AIM,CXXC finger protein 9,CXXC-type zinc finger protein 9,CXXC9,DNA (cytosine 5 ) methyltransferase 1,DNA (cytosine-5)-methyltransferase 1,DNA methyltransferase 1,DNA methyltransferase HsaI,DNA methyltransferase M.HsaI.,DNA MTase,DNA MTase HsaI,DNMT 1,DNMT,Dnmt1,DNMT1,Dnmt1o,FLJ16293,HSN1E,M.HsaI,MCMT,Met1,MGC104992,mMmul,MommeD2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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