Anti-Human DNA Ligase1 Polyclonal Antibody

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03537
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human DNA Ligase I
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P18858
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names DNA ligase 1,DNA ligase I,DNLI1,LIG 1,lig1,Ligase I DNA ATP dependent,MGC117397,MGC130025,Polydeoxyribonucleotide synthase [ATP] 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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