Anti-Human DMGDH Polyclonal Antibody

This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03534
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human DMGDH
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9UI17
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names Dimethylglycine dehydrogenase,Dimethylglycine dehydrogenase,mitochondrial,Dmgdh,M2GD,ME2GLYDH,mitochondrial
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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