Anti-Human DISC1 Polyclonal Antibody

This gene encodes a protein with multiple coiled coil motifs which is located in the Nucleus, Cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11357
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human DISC1
Specificity Ubiquitous. Highly expressed in the dentate gyrus of the hippocampus. Also expressed in the temporal and parahippocampal cortices and cells of the white matter.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9NRI5
Concentration 0.1 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names C1orf136,DISC1,DISC1,Disrupted in schizophrenia 1,Disrupted in schizophrenia 1 protein,KIAA0457,RP4-730B13.1,SCZD9
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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