Anti-Human DEFA1 Polyclonal Antibody

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12006
Size 200μl
Host Type Rabbit
Immunogen Recombinant protein of human DEFA1
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P59665
Concentration 0.3 mg/mL
Dilution IHC 1:10-1:50
Formulation
Application IHC,ELISA
Other Names DEF1,DEF3,DEFA1,DEFA2,DEFA3,Defensin alpha 1,Defensin alpha 2,Defensin alpha 3,HNP1,HNP3,HP1,HP3,MRS,Neutrophil defensin 1,Neutrophil defensin 2,Neutrophil defensin 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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