Anti-Human CXCL13 Polyclonal Antibody

B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.CXCL13 (C-X-C Motif Chemokine Ligand 13) is a Protein Coding gene. Diseases associated with CXCL13 include Asymptomatic Neurosyphilis and Angioimmunoblastic T-Cell Lymphoma. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include protein heterodimerization activity and chemokine activity.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06356
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human BLC.
Specificity Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen.
Isotype IgG
Reacitivity Human
Clone
Uniprot O43927
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names ANGIE,ANGIE2,B cell attracting chemokine 1,B cell-attracting chemokine 1,B lymphocyte chemoattractant,B-cell chemoattractant,B-cell-attracting chemokine 1,B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1),BCA-1,BLC,BLR1L,C-X-C motif chemokine 13,Chemokine (C-X-C motif) ligand 13,Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant),Chemokine,CXC motif,ligand 13,CXC chemokine BLC,CXCL13,CXL13,SCYB13,Small inducible cytokine B subfamily (Cys-X-Cys motif),member 13 (B-cell chemoattractant),Small inducible cytokine B13,Small inducible cytokine subfamily B,member 13,Small-inducible cytokine B13
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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