Anti-Human CPN1 Polyclonal Antibody

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.CPN1 (Carboxypeptidase N Subunit 1) is a Protein Coding gene. Diseases associated with CPN1 include Carboxypeptidase N Deficiency and Pyelitis. Among its related pathways are Androstenedione and testosterone biosynthesis and metabolism p.1 and Metabolism of proteins. GO annotations related to this gene include metallocarboxypeptidase activity and carboxypeptidase activity. An important paralog of this gene is CPE.