Anti-Human CNGA1 Polyclonal Antibody

The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10960
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human CNGA1
Specificity Rod cells in the retina.
Isotype IgG
Reacitivity Human
Clone
Uniprot P29973
Concentration 0.4 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names cGMP gated cation channel alpha 1,cGMP-gated cation channel alpha-1,CNCG,CNCG1,CNG 1,CNG channel alpha 1,CNG channel alpha-1,CNG-1,CNG1,Cnga1,CNGA1,Cyclic nucleotide gated cation channel 1,Cyclic nucleotide gated channel alpha 1,Cyclic nucleotide gated channel photoreceptor,Cyclic nucleotide-gated cation channel 1,Cyclic nucleotide-gated channel alpha-1,Cyclic nucleotide-gated channel,Interleukin 1 homologue,OTTHUMP00000218675,OTTHUMP00000223313,OTTHUMP00000223314,photoreceptor,RCNC1,RCNCa,RCNCalpha,Rod photoreceptor cGMP gated channel subunit alpha,Rod photoreceptor cGMP-gated channel subunit alpha,RP49
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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