Anti-Human Cleaved-KLK11 (I54) Polyclonal Antibody

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02139
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human KLK11
Specificity Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level).
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9UBX7
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names Hippostasin,hK11,Kallikrein 11,Kallikrein 11 isoform 1 preproprotein,Kallikrein 11 isoform 2 precursor,Kallikrein 11 precursor,Kallikrein related peptidase 11,Kallikrein-11 inactive chain 2,KLK 11,Klk11,KLK11,MGC33060,Protease serine 20 trypsin like,Protease serine trypsin like,PRSS20,Serine protease 20,TLSP,Trypsin like protease,Trypsin-like protease
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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