Anti-Human CFL1 Polyclonal Antibody

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03760
Size 100μl
Host Type Rabbit
Immunogen Recombinant human Homeobox protein Cofilin-1 protein
Specificity Widely distributed in various tissues.
Isotype IgG
Reacitivity Human
Clone
Uniprot P23528
Concentration 2 mg/mL
Dilution WB 1:500-1:1000
Formulation
Application WB
Other Names 18 kDa phosphoprotein,CFL 1,CFL,CFL1,COF1,Cofilin 1,Cofilin 1 non muscle,Cofilin,Cofilin non muscle isoform,Cofilin-1,epididymis secretory protein Li 15,HEL-S-15,non-muscle isoform,p18
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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