Anti-Human CDCP1 Polyclonal Antibody

This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03430
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human CDCP1
Specificity Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9H5V8
Concentration 1 mg/mL
Dilution WB 1:500-1:1000
Formulation
Application WB
Other Names 9030022E12Rik,AA409659,CD 318,CD_antigen=CD318,CD318,CD318 antigen,CDCP 1,Cdcp1,CDCP1,CUB domain containing protein 1,CUB domain-containing protein 1,E030027H19Rik,FLJ13772,FLJ22375,FLJ22969,Membrane glycoprotein gp140,MGC31813,OTTHUMP00000164120,OTTHUMP00000209568,RGD1305578,SIMA 135,SIMA135,Subtractive immunization M plus HEp3 associated 135 kDa protein,Subtractive immunization M plus HEp3-associated 135 kDa protein,Transmembrane and associated with src kinases,TRASK
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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