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Anti-Human CD88 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02598
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human CD88 around the non-phosphorylation site of Ser338.
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P21730
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names ANAPHYLATOXIN RECEPTOR,C5a anaphylatoxin chemotactic receptor,C5a anaphylatoxin receptor,C5A,C5a ligand,C5a-R,C5aR,C5AR,c5ar1,C5R1,CD88,CD88 antigen,Complement component 5 receptor 1,Complement component 5 receptor 2,Complement component 5a receptor 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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