Anti-Human CD59 Polyclonal Antibody

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06397
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human CD59.
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P13987
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names 16.3A5,1F5,1F5 antigen,20 kDa homologous restriction factor,CD 59,CD_antigen=CD59,CD59,CD59 antigen,CD59 antigen complement regulatory protein ,CD59 antigen p18 20,CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5,EJ16,EJ30,EL32 and G344),CD59 glycoprotein,CD59 molecule,CD59 molecule complement regulatory protein,CD59,Cd59a,Complement regulatory protein,EJ16,EJ30,EL32,FLJ38134,FLJ92039,G344,HRF 20,HRF-20,HRF20,Human leukocyte antigen MIC11,Ly 6 like protein,Lymphocytic antigen CD59/MEM43,MAC inhibitory protein,MAC IP,MAC-inhibitory protein,MAC-IP,MACIF,MACIP,MEM43,MEM43 antigen,Membrane attack complex (MAC) inhibition factor,Membrane attack complex inhibition factor,Membrane inhibitor of reactive lysis,MGC2354,MIC11,MIN1,MIN2,MIN3,MIRL,MSK21,p18 20,Protectin,Surface antigen recognized by monoclonal 16.3A5,T cell activating protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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