Anti-Human CD54 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA09543
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human ICAM1
Specificity
Isotype	IgG
Reacitivity	Human
Clone
Uniprot	P05362
Concentration	0.4 mg/mL
Dilution	WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application	WB,IHC,ELISA
Other Names	Antigen identified by monoclonal BB2,BB 2,BB2,CD 54,CD_antigen=CD54,CD54,Cell surface glycoprotein P3.58,Human rhinovirus receptor,ICAM 1,ICAM-1,ICAM1,ICAM1,intercellular adhesion molecule 1 (CD54),human rhinovirus receptor,Intercellular adhesion molecule 1,Major group rhinovirus receptor,MALA 2,MALA2,MyD 10,MyD10,P3.58,Surface antigen of activated B cells,BB2
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human CD54 Polyclonal Antibody

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