Anti-Human CD328 Polyclonal Antibody

Siglec-7, which is highly expressed in monocytes and resident blood cells but not in parenchymatous cells, mediates inhibition of natural killer cell cytotoxicity. Due to alternative splicing events, two isoforms exist for Siglec-12, namely SLG-L (the long isoform) and SLG-S (the shorter isoform). These isoforms are differentially expressed with the longer isoform predominantly found in small intestine, spleen and bone marrow, and the shorter isoform predominantly found in small intestine, spleen and adrenal gland.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10989
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SIGLEC7
Specificity Predominantly expressed by resting and activated natural killer cells and at lower levels by granulocytes and monocytes. High expression found in placenta, liver, lung, spleen, and peripheral blood leukocytes.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9Y286
Concentration 0.7 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names Adhesion inhibitory receptor molecule 1,Adhesion inhibitory receptor molecule 1,siglec 7,AIRM 1,AIRM-1,AIRM1,CD328,CD328 antigen,CDw328,D siglec,D-siglec,HLDA 8,p75,p75/AIRM1,QA79,QA79 membrane protein,Sialic acid binding Ig like lectin 7,Sialic acid binding immunoglobulin like lectin 7,Sialic acid-binding Ig-like lectin 7,SIGL7,Siglec-7,SIGLEC19P,SIGLEC7,SIGLECP2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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