Anti-Human CD328 Polyclonal Antibody

Sialic acid-binding Ig-like lectin 7 is a protein that in humans is encoded by the SIGLEC7 gene. SIGLEC7 has also been designated as CD328 (cluster of differentiation 328). Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09576
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SIGLEC7
Specificity Predominantly expressed by resting and activated natural killer cells and at lower levels by granulocytes and monocytes. High expression found in placenta, liver, lung, spleen, and peripheral blood leukocytes.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9Y286
Concentration 0.5 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names Adhesion inhibitory receptor molecule 1,Adhesion inhibitory receptor molecule 1,siglec 7,AIRM 1,AIRM-1,AIRM1,CD328,CD328 antigen,CDw328,D siglec,D-siglec,HLDA 8,p75,p75/AIRM1,QA79,QA79 membrane protein,Sialic acid binding Ig like lectin 7,Sialic acid binding immunoglobulin like lectin 7,Sialic acid-binding Ig-like lectin 7,SIGL7,Siglec-7,SIGLEC19P,SIGLEC7,SIGLECP2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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