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Anti-Human CD307 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.FCRL5 (Fc Receptor Like 5) is a Protein Coding gene. Diseases associated with FCRL5 include Hairy Cell Leukemia and Burkitt Lymphoma. An important paralog of this gene is FCRL3.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06410
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human CD307.
Specificity Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B cells and down-regulated in germinal center cells (at protein level).
Isotype IgG
Reacitivity Human
Clone
Uniprot Q96RD9
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names BXMAS1,CD307 antigen,CD307e,Fc receptor homolog 5,Fc receptor like 5,Fc receptor-like protein 5,FcR-like protein 5,FcRH5,FcRL5,FCRL5,Immune receptor translocation-associated protein 2,Immunoglobulin receptor translocation associated gene 2 protein,Immunoglobulin superfamily receptor translocation associated gene 2 protein,IRTA2,UNQ503/PRO820
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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