Anti-Human CD303 Polyclonal Antibody

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04027
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide from human protein
Specificity Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q8WTT0
Concentration 1mg/mL
Dilution IHC 1:50-200, ELISA 1:10000-20000
Formulation
Application IHC-p,ELISA
Other Names C-type lectin domain family 4 member C (Blood dendritic cell antigen 2) (BDCA-2) (C-type lectin superfamily member 7) (Dendritic lectin) (CD antigen CD303)
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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