Anti-Human CD28 Polyclonal Antibody

The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.CD28 (CD28 Molecule) is a Protein Coding gene. Diseases associated with CD28 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and CTLA4 Signaling. GO annotations related to this gene include identical protein binding and SH3/SH2 adaptor activity. An important paralog of this gene is CTLA4.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06390
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human CD28.
Specificity Expressed in T-cells and plasma cells, but not in less mature B-cells.
Isotype IgG
Reacitivity Human
Clone
Uniprot P10747
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names CD 28,CD28,CD28 antigen,CD28 molecule,CD28,MGC138290,T cell antigen CD28,T cell specific surface glycoprotein,T cell specific surface glycoprotein CD28,T-cell-specific surface glycoprotein CD28,TP44
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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