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Anti-Human CD275 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
ICOS ligand is a protein that in humans is encoded by the ICOSLG gene. ICOSLG has also been designated as CD275 (cluster of differentiation 275). Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11480
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human ICOSLG
Specificity Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.
Isotype IgG
Reacitivity Human
Clone
Uniprot O75144
Concentration 0.4 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names B7 H2,B7 homolog 2,B7 homologue 2,B7 like protein Gl50,B7 related protein 1,B7-H2,B7-like protein Gl50,B7-related protein 1,B7H2,B7RP 1,B7RP-1,B7RP1,CD 275,CD275,CD275 antigen,GL 50,GL50,ICOS L,ICOS LG,ICOS ligand,ICOSL,ICOSL,Icoslg,Inducible T cell co stimulator ligand,KIAA0653,LICOS,Transmembrane protein B7 H2 ICOS ligand
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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