Anti-Human CD275 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene is ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. May be play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA04988
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide from human protein
Specificity	Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.
Isotype	IgG
Reacitivity	Human
Clone
Uniprot	O75144
Concentration	1mg/mL
Dilution	IHC 1:50-200, ELISA 1:10000-20000
Formulation
Application	IHC-p,ELISA
Other Names	B7 H2,B7 homolog 2,B7 homologue 2,B7 like protein Gl50,B7 related protein 1,B7-H2,B7-like protein Gl50,B7-related protein 1,B7H2,B7RP 1,B7RP-1,B7RP1,CD 275,CD275,CD275 antigen,GL 50,GL50,ICOS L,ICOS LG,ICOS ligand,ICOSL,ICOSL,Icoslg,Inducible T cell co stimulator ligand,KIAA0653,LICOS,Transmembrane protein B7 H2 ICOS ligand
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human CD275 Polyclonal Antibody

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