Anti-Human CD109 Polyclonal Antibody

This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08603
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human CD109
Specificity Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 5 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q6YHK3
Concentration 0.4 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names 150 KDa TGF beta 1 binding protein,150 KDa TGF-beta-1-binding protein,7D1,8A3,Activated T cell marker CD109,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7,CD 109,CD109,CD109 antigen,CD109,CPAMD7,DKFZp762L1111,E123,FLJ38569,FLJ41966,Gov system alloantigens on platelets,p180,Platelet specific Gov antigen,Platelet-specific Gov antigen,r150,RP11 525G3.1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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