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Anti-Human CCDC99 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02520
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human CCDC99
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot Q96EA4
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:40000
Formulation
Application WB,ELISA
Other Names AA409762,Arsenite related gene 1 protein,Arsenite-related gene 1 protein,CCDC 99,Ccdc99,Coiled coil domain containing 99,Coiled-coil domain-containing protein 99,FLJ20364,FLJ40690,hSpindly,MGC124977,Protein Spindly,rhabdomyosarcoma antigen MU RMS 40.4A,Rhabdomyosarcoma antigen MU-RMS-40.4A,Rrhabdomyosarcoma antigen protein MU RMS 40.4A,SPDL1,SPDLY,Spindle apparatus coiled coil domain containing protein 1,Spindle apparatus coiled coil protein 1,Spindly,Spindly homolog
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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