Anti-Human CBR1 Polyclonal Antibody

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02433
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Carbonyl Reductase 1.
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P16152
Concentration 1 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:20000
Formulation
Application WB,IHC,ELISA
Other Names 15 hydroxyprostaglandin dehydrogenase [NADP+],15-hydroxyprostaglandin dehydrogenase [NADP+],Carbonyl reductase [NADPH] 1,Carbonyl Reductase 1,CBR 1,CBR1,CBR1,CRN,NADPH dependent carbonyl reductase 1,NADPH-dependent carbonyl reductase 1,Prostaglandin 9 ketoreductase,Prostaglandin 9-ketoreductase,Prostaglandin E(2) 9 reductase,Prostaglandin-E(2) 9-reductase,SDR21C1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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