Anti-Human BID Polyclonal Antibody

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11642
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human BID
Specificity Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
Isotype IgG
Reacitivity Human
Clone
Uniprot P55957
Concentration 0.5 mg/mL
Dilution WB 1:200-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Apoptic death agonist,Apoptotic death agonist BID,BH3 interacting domain death agonist,BH3 interacting domain death agonist p11,BH3 interacting domain death agonist p13,BH3 interacting domain death agonist p15,BH3-interacting domain death agonist p11,BID,BID isoform ES(1b),BID isoform L(2),BID isoform Si6,BID,Desmocollin type 4,FP497,Human BID coding sequence,MGC15319,MGC42355,p11 BID,p13 BID,p15 BID,p22 BID
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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