Anti-Human BCL2L12 Polyclonal Antibody

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11487
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human BCL2L12
Specificity Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9HB09
Concentration 0.2 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names B2L12,BCL 2 like 12 (proline rich),BCL 2 like 12,BCL 2 like 12 isoform 1,Bcl 2 like 12 protein,Bcl 2 related proline rich protein,Bcl-2-like protein 12,Bcl-2-related proline-rich protein,BCL2 like 12 (proline rich),BCL2 like 12,BCL2 like 12 isoform 1,Bcl2 like 12 protein,Bcl2 related proline rich protein,Bcl2-L-12,BCL2L12,BPR,MGC120313,MGC120314,MGC120315
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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