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Anti-Human BAG1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02322
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Bag-1.
Specificity Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis. Isoform 4 is expressed in several types of tumor cell lines, and at consistently high levels in leukemia and lymphoma cell lines. Isoform 1 is expressed in the prostate, breast and leukemia cell lines. Isoform 3 is the least abundant isoform in tumor cell lines (at protein level).
Isotype IgG
Reacitivity Human
Clone
Uniprot Q99933
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names Bag 1,BAG family molecular chaperone regulator 1,BAG-1,BAG1,BAG1,BCL 2 Associated Athanogene 1,BCL 2 associated athanogene,BCL 2 binding athanogene 1,Bcl-2-associated athanogene 1,BCL2 associated athanogene 1,BCL2 associated athanogene,Glucocorticoid receptor-associated protein RAP46,HAP1,Haptoglobin,RAP 46,RAP46
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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